Tylenol 4 contains which combination?

Tylenol 4 contains which combination?

• A. 300 mg Acetaminophen + 8 mg Codeine
• B. 300 mg Acetaminophen + 60 mg Codeine
• C. 300 mg Acetaminophen + 15 mg Codeine
• D. 300 mg Acetaminophen + 30 mg Codeine

Answer: (B)

Tylenol 4 is a fixed-dose combination analgesic that pairs acetaminophen with an opioid to provide stronger pain relief than acetaminophen alone. The standard formulation for Tylenol 4 is 300 mg of acetaminophen combined with 60 mg of codeine per tablet. The codeine is a prodrug that, after metabolic activation, provides additional opioid analgesia, which is why this product is used for moderate to moderately severe pain. Among the options, the only one that matches the familiar Tylenol 4 strength is the tablet containing 300 mg acetaminophen and 60 mg codeine. The other listed codeine amounts correspond to other (less potent) Tylenol-with-codeine products, not Tylenol 4. Keep in mind the acetaminophen dose adds up with repeated dosing, so be mindful of the daily maximum to avoid liver toxicity, and be aware that codeine carries risks of sedation and dependence and is affected by individual metabolic differences.

Tylenol 4 is a fixed-dose combination analgesic that pairs acetaminophen with an opioid to provide stronger pain relief than acetaminophen alone. The standard formulation for Tylenol 4 is 300 mg of acetaminophen combined with 60 mg of codeine per tablet. The codeine is a prodrug that, after metabolic activation, provides additional opioid analgesia, which is why this product is used for moderate to moderately severe pain.

Among the options, the only one that matches the familiar Tylenol 4 strength is the tablet containing 300 mg acetaminophen and 60 mg codeine. The other listed codeine amounts correspond to other (less potent) Tylenol-with-codeine products, not Tylenol 4.

Keep in mind the acetaminophen dose adds up with repeated dosing, so be mindful of the daily maximum to avoid liver toxicity, and be aware that codeine carries risks of sedation and dependence and is affected by individual metabolic differences.