Which medication ends with -glitazone and improves insulin sensitivity?

Which medication ends with -glitazone and improves insulin sensitivity?

• A. Metformin
• B. Pioglitazone
• C. Acarbose
• D. Sitagliptin

Answer: (B)

Ending with -glitazone points to the thiazolidinedione class, which are insulin sensitizers. Pioglitazone activates PPAR-γ receptors, leading to changes in fat, muscle, and liver that improve how effectively tissues respond to insulin. This makes glucose uptake by cells more efficient, reducing insulin resistance. Other drugs in the options work differently: metformin mainly lowers liver glucose production, acarbose slows carbohydrate absorption in the gut, and sitagliptin enhances incretin effects to adjust insulin and glucagon. So the one that ends with -glitazone and improves insulin sensitivity is pioglitazone.

Ending with -glitazone points to the thiazolidinedione class, which are insulin sensitizers. Pioglitazone activates PPAR-γ receptors, leading to changes in fat, muscle, and liver that improve how effectively tissues respond to insulin. This makes glucose uptake by cells more efficient, reducing insulin resistance. Other drugs in the options work differently: metformin mainly lowers liver glucose production, acarbose slows carbohydrate absorption in the gut, and sitagliptin enhances incretin effects to adjust insulin and glucagon. So the one that ends with -glitazone and improves insulin sensitivity is pioglitazone.