Which suffix is typical for fluoroquinolones?

Prepare for the INBDE Pharmacology Test with flashcards and multiple-choice questions, each question has hints and explanations. Get ready for your exam!

Multiple Choice

Which suffix is typical for fluoroquinolones?

Explanation:
Suffixes in antibiotic names help you spot the class. Fluoroquinolones end with -floxacin, so drugs like ciprofloxacin, levofloxacin, and moxifloxacin fit this group. This naming pattern reflects a shared mechanism—these drugs inhibit bacterial DNA gyrase and topoisomerase IV, disrupting DNA replication. The other endings point to different antibiotic classes: -cycline is seen with tetracyclines, -mycin is common for macrolides (and some other older agents), and -cillin marks penicillins, a beta-lactam class. So the -floxacin ending is the telltale sign of fluoroquinolones.

Suffixes in antibiotic names help you spot the class. Fluoroquinolones end with -floxacin, so drugs like ciprofloxacin, levofloxacin, and moxifloxacin fit this group. This naming pattern reflects a shared mechanism—these drugs inhibit bacterial DNA gyrase and topoisomerase IV, disrupting DNA replication. The other endings point to different antibiotic classes: -cycline is seen with tetracyclines, -mycin is common for macrolides (and some other older agents), and -cillin marks penicillins, a beta-lactam class. So the -floxacin ending is the telltale sign of fluoroquinolones.

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